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Designing efficient single-metal atom biocatalysts at the atomic structure level

This helps explain why simply adding SAMe, methionine or methylated vitamins may fail when the underlying metabolic and elimination burden has not been addressed

Footnotes Abbreviations: CAP = community-acquired pneumonia, COPD = chronic obstructive pulmonary disease, CT = computed tomography, IL = interleukin, MDA = malondialdehyde, NAC = N-acetylcysteine, ROS = reactive oxygen species, SOD = superoxide dismutase, TAOC = total antioxidant capacity, TNF = tumor necrosis factor

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Metabolic control analysis of the Warburg-effect in proliferating vascular smooth muscle cells