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From the approval of Orlistat (Xenical) in 1999, which focused on reducing dietary fat absorption, to the emergence of highly effective incretin-based therapies such as liraglutide (Saxenda), semaglutide (Wegovy), and tirzepatide (Zepbound), we have witnessed a fundamental shift in how obesity is understood and treated

Oral semaglutide showed cardiovascular safety profile, with significant reduced risk of death from cardiovascular events

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In those years, Wegovy and Mounjaro, respectively, were the highest-volume and highest-utilization drivers of this overall trend.

PlexusDx explains the evidence, timeline, and next steps

Here are 7 things to consider before you drink alcohol when youre on one of these drugs.