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432 High p53 activity reduces the transcription of SLC7A11 and the antioxidant potential of frataxin-deficient cells, therefore, inhibiting P53 activity to improve system Xc and GSH content may be a potential therapeutic strategy to combat oxidative stress and possible ferroptosis in Friedreichs Ataxia
10.1042/0264-6021:3510341 4 AllocatiN.FedericiL.MasulliM.Di IlioC
(2015) 104:845856.e8
ApplyORAC Creammorning and night on clean skin and protect with SPF
Studies on intestinal permeability show that NAG supplementation significantly improves transepithelial electrical resistance (TEER)a primary measurement of barrier integrity
More help Evidence Assessment Addressess the biological plausibility, empirical support, and quantitative understanding from each KER in an AOP
