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Insulin resistance can be also interpreted as a (mal)adaptive response, at least initially aimed at countering excessive accumulation of energy metabolites in tissues [28, 29]
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Heated the reaction mixture to 75- 80C and stirred for 30 min at the same temperature

Int J Mol Sci 2021;22:2973
At 48 weeks, relative liver fat reductions reached -81.7% and -86.0% with 8mg and 12mg doses respectively
