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doi: 10.3390/nu7064139 [DOI] [PMC free article] [PubMed] [Google Scholar] 26

Although the trials with a single dose (NCT01357070, NCT05146804) showed changes in biomarkers, longer intervention may be required for SFN to have significant clinical effects

Cell (2020) 182:71321

Modern medicine has also found that the pathogenesis of HPS may be related to the release of various cytokines in the body resulting in angiogenesis and pulmonary vasodilation caused by cirrhosis

[,] Conventionally, bilirubin must be conjugated to glucuronic acid before excretion into bile
Shah AA, Kamal MA, Akhtar S (2021) Tumor angiogenesis and VEGFR-2: mechanism, pathways and current biological therapeutic interventions
