glp 1 is it safe GLP-1 Agonists for Weight Loss: or Risky? are glp-1 shots safe GLP-1s:
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10.1089/dia.2011.0050 31 DicksonS

Glucagon Like Peptide-1 and Its Receptor in Human Brain: Distribution of Expression, Functional Implications, Age Related Changes & Species Specific Characteristics
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Recently, the results of a landmark randomized controlled trial showed treatment with tirzepatide (15 mg subcutaneous/week), a dual GLP-1R/GIP receptor (GIPR) agonist, caused an 18% placebo-subtracted weight loss (21% total weight loss) at 72 weeks in people with obesity (6)