glp 1 diabete GLP-1 for Weight Loss and Diabetes Mechanisms of action of GLP-1RA.

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The brain reward system plays a critical role in perpetuating behaviors that are important for survivalfeeding, reproductive behavior, etc.through release of dopamine, responsible for the pleasure sensation

Those qualifying conditions include type 2 diabetes, hypertension, high cholesterol, obstructive sleep apnea, cardiovascular disease, polycystic ovary syndrome, and non-alcoholic fatty liver disease

Connecting those anecdotal accounts with the fact that there are GLP-1 receptors in the brain in regions that modulate reward processing, and therefore might affect cravings, Al-Aly and his collaborators investigated whether GLP-1s could treat all substance use disorders

*FOR ORAL SEMAGLUTIDE USED FOR WEIGHT-LOSS SOURCE: New England Journal of Medicine

10.1016/j.jdiacomp.2023.108416 [DOI] [PubMed] [Google Scholar] 85.Eissa RG, Eissa NG, Eissa RA, Diab NH, Abdelshafi NA, Shaheen MA, Elsabahy M, Hammad SK (2023) Oral proniosomal Amitriptyline and liraglutide for management of diabetic neuropathy: exceptional control over hyperglycemia and neuropathic pain