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A GST mutant in which four glutamine residues were replaced with asparagine (GST 4QN ) exhibited a glutathione binding affinity similar to that of wild-type GST and could be purified by glutathione affinity chromatography

Shikonin-induced necroptosis in nasopharyngeal carcinoma cells via ROS overproduction and upregulation of RIPK1/RIPK3/MLKL expression

Metallodrugs administered by injection directly enter the bloodstream and are rapidly distributed to various organs, especially tumor tissues

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Moreover, there may be an association between environmental toxins such as heavy metals (e.g., arsenic) and sleep disturbance [82,83]

In spite of those appealing features of MnO 2 nanostructures, some currently developed MnO 2 nanostructures are still lack of well-defined morphology, such as irregular nanosheets or uneven nanoparticles, which are not desirable for optimizing drug loading and controlling drug release