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Surprisingly, in contrast to the favorable metabolic activity of sitagliptin evident in younger mice, sitagliptin failed to improve lipid tolerance in older mice

This was not the case for other intestinal hormones such as GIP

Effect of Initial Combination Therapy With Sitagliptin, a Dipeptidyl Peptidase-4 Inhibitor, and Metformin on Glycemic Control in Patients With Type 2 Diabetes

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These symptoms may include difficulties in breathing problems, feeding, or increased irritability

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