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[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Wang M., Tan Y., Shi Y., Wang X., Liao Z., Wei P

While these medications had impactful weight loss outcomes, with mean weight reduction in trials ranging from 7 to 10% [3,4,5], they lacked substantial evidence of improvement in cardiovascular outcomes

This muscle loss can manifest in subtle but meaningful ways: a gradual decline in strength, slower recovery from activity, reduced endurance, and increased fatigue

Clinical trials did not identify back pain occurring at significantly higher rates compared to placebo

However, this phenomenon is rather a restoration of the first-phase insulin response due to the concomitant weight loss of typically 56 kg

Severe cases often result from vagus nerve damage, which controls stomach muscles
