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Together with glucagon, these nuanced actions of GLP-1 and GIP illustrate the complexity of incretin crosstalk in maintaining metabolic homeostasis

Do not stop treatment abruptly without medical guidance, as this may affect glycaemic control or weight management outcomes

Among over 750 000 pregnancies, researchers found that these medications were associated with increased preterm birth risk, but this risk was only present when the medication was used for diabetes treatment, not when used for weight management

Joint pain decreases

It becomes a clinical concern if: Measured temperature exceeds 38.5C (101.3F) this crosses into fever territory and warrants evaluation for other causes Sweating is severe enough to disrupt sleep or require clothing changes Flushing is persistent rather than transient lasting more than 46 hours Palpitations accompany the warmth glucagon increases heart rate slightly

[DOI] [PMC free article] [PubMed] [Google Scholar] 9.Dean RG, Burrell LM