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"Through this research, GLP-1 RAs not only benefited patient outcomes, but we also saw a decrease in LDL, triglycerides, hospital admissions

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Glucagon-like peptide-1 (GLP-1) receptor agonists were touted as breakthrough drugsin 2023 and their popularity has soared since. More than 4 million items of tirzepatide and semaglutide were dispensed on the NHS in England in 2025/20261, while around2.5 million people each monthaccessed GLP-1s privately at the end of 2025, according to James Kingsland, chair of []

Perhaps, we will be able to help some people to avoid side effects with one medicine by using a different one, or by using lower doses with specific combinations

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Based on promising findings from this initial consumer study, Pendulum is planning additional clinical trials to further our scientific understanding