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Glp1r / mice, and, to a greater extent, Glp1r / : Gipr / mice, exhibit defective glucose-stimulated insulin secretion, subnormal upregulation of insulin gene expression in response to high-fat diet (HFD) feeding, and impaired glucose tolerance (3, 4)

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As well as increasing the risk of developing sleep apnoea, being overweight can lead to metabolic changes that disrupt the sleep-wake cycle

It works by mimicking one specific hormone: GLP-1 (glucagon-like peptide-1)

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