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Key highlights: Once-daily oral administration Up to 11.8% weight loss over 36 weeks Focus on broader cardiometabolic health outcomes Advancement into Phase III development As obesity remains one of the most significant global health challenges, innovation in oral GLP-1 therapies could help improve accessibility and patient adherence while expanding treatment options beyond injectable therapies

The truth about GLP-1 weight loss medications and their impact on athletic performance

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Aims/hypothesis Metformin is the only approved oral agent for youth with type 2 diabetes but its mechanism of action remains controversial

US gut health company Pendulum Therapeutics has introduced Gut Fuel, a doctor-formulated prebiotic fibre and polyphenol powder combining resistant potato starch, baobab, acacia, oat beta-glucan and grape seed extract to support the microbiome, metabolic function and natural GLP-1 pathways