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Mutations in PNPLA3 antagonize normal proteasomal degradation and increase the risk of MASLD and its severity

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10.1001/jamaoncol.2015.1546 [EL 2

If particles persist, try these steps in order: ensure the solvent is at room temperature (cold water dissolves peptides more slowly), increase swirling time to 30 minutes, gently roll the vial between your palms to warm slightly, and as a last resort, place the vial in a room-temperature water bath for 5 minutes