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Type I interferon receptor deficiency prevents murine Sjogren's syndrome

doi: 10.1016/j.crvi.2005.05.002

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Metab Brain Dis 39(3):373385 Dinkova-Kostova AT, Kostov RV, Kazantsev AG (2018) The role of Nrf2 signaling in counteracting neurodegenerative diseases

Low levels ROS, including hydrogen peroxide, are needed for essential cellular processes, such as growth factor-mediated signaling, formation of necessary protein-disulfide bonds, and regulation of normal mitochondrial function [16, 17]

For example, hedyotis diffusa injection can induce ferroptosis in lung cancer by inhibiting Bcl2, promoting Bax and activating VDAC2/3 channel, thereby increasing the release of ROS [247]