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Berndt-Zipfel C, Michelson G, Dworak M, et al

At present, seven triple receptor agonists, including Retatrutide (LY3437943), SAR441255 and xGLP/GCG/GIP-32, have entered the clinical research stage

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The anti-inflammatory effects of GLP-1 receptor agonists appear to operate through pathways that are activated at lower receptor occupancy levels than those required for metabolic effects
