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A retrospective study had reported low placental selenium concentrations in 49 mothers affected by fetal growth restriction, compared to 36 healthy normal birth weight controls [60], whereas others have reported higher [61, 62] or unchanged concentrations [63]

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STI suggests a tolerance mechanism that allows plants to retain development even in the presence of abiotic factors such as hazardous metal levels 48

10.1126/science.276.5309.122 Summary Keywords busulfan, population pharmacokinetics, glutathione S-transferase activity, precision dosing, pediatric transplantation, virtual clinical trial Citation Cao D, Qian X, Wang P, Zheng X, Huang S, Wei Z, Jiang W, Yu L, Jiang X, Yu Y, Mao J and Zhai X (2025) Semi-mechanistic population pharmacokinetic model incorporating glutathione S-transferase activity for personalized busulfan dosing in pediatric allogeneic hematopoietic cell transplantation

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