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Extensions or other delay taken by the applicant can reduce or eliminate the extension

Failing to account for this when switching vial sizes is one of the most common and dangerous reconstitution errors

Can I get a baseline hearing test before starting a high-risk medication

[107] Contraindications and Long-Term Concerns Semaglutide is contraindicated in patients with a personal or family history of medullary thyroid carcinoma or Multiple Endocrine Neoplasia syndrome type 2, due to rodent studies demonstrating thyroid C-cell tumors with GLP-1 receptor agonists, though human data show no elevated risk

In the unmatched analysis, GLP-1 agonist use was linked to lower breast cancer incidence (OR, 0.65)

Monitoring your health while using a GLP-1 receptor agonist is important, and certain symptoms or situations, such as the ones below, should prompt a consultation with a doctor: New or worsening gastrointestinal symptoms, such as persistent nausea, vomiting, diarrhoea, or signs of dehydration 7 , 27