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Beyond weight loss, GLP-1 medications appear to have direct effects on how the liver produces and processes cholesterol

Mounjaro is a dual-targeting drug as it also targets the glucose-dependent insulinotropic polypeptide (GIP) receptor, making it the first-in-class GIP/GLP-1 receptor agonist for the treatment of type 2 diabetes

The 503A patient-specific compounding pathway would remain as the narrower, intact legal route

Simultaneously, these agents suppress glucagon secretion from pancreatic alpha cells, further helping to regulate blood glucose levels

One has to balance all of this with the understanding that these drugs will cause weight loss in any patient who takes them, he says

Infusions with GIP(3-30)NH 2 in healthy individuals during a mixed meal test or an oral glucose tolerance test as well as in persons with obesity in the fasting state do not affect glucagon levels (87, 90)