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doi: 10.1111/ajt.15219

Zoccali C, Curatola G, Panuccio V, Tripepi R, Pizzini P, Versace M,

Phagocytic astrocytes: emerging from the shadows of microglia

Where both homocysteine and glutathione are unusually low, it may indicate impaired folate metabolism or reduced activity of enzymes involved in one-carbon metabolism, such as DHFR or MTHFR, rather than representing an ideal metabolic state
