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164 However, in a larger meta-analysis of 43 studies, there was no difference in major gastrointestinal bleeding with apixaban compared with warfarin

E., Gaebel, G., Hempel, V., Krug, W., and Kohn, H

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Major metabolites found were trimethylamine N-oxide, primarily in urine (8% to 49% of the administered dose) and [ 3H]--butyrobetaine, primarily in feces (0.44% to 45% of the administered dose)