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9,394,338 Applications Treatment for Alzheimers and other neurodegenerative diseases Key Benefits & Differentiators Increased stability: Resistance to -glutamyl transpeptidase (-GT) breakdown leads to extended antioxidant activity Replicates endogenous GSH activity: Crosses the blood-brain barrier and mimics key glutathione (GSH) functions Technology Overview Oxidative stress and plaque formation from glycation are key features of numerous neurodegenerative diseases, including Alzheimers disease

2016;310:R33R40

NAC was also able to significantly restore lung superoxide dismutase (SOD) and catalase (CAT) levels, which decreased 3 hours after phosgene exposure

doi: 10.1016/j.pep.2010.12.004

Elachouri, G

Detection of glutathione in cell culture medium A total 20 l of CAF-, LNCaP- or non-conditioned medium was mixed with 50 l acetone and incubated at 20 C overnight