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As we identified GPX4 as a functional target of three out of four senolytic chloroacetamides, we wanted to understand how widely senolytic electrophilic compounds might induce ferroptosis

Research has found that supplementing with glutathione or NAC can improve overall glutathione levels in the body

In brief, protein aliquots of mouse liver were added in protein low bind tubes, followed by precipitating the protein with 10-fold acetonitrile