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doi: 10.1073/pnas.93.1.131

It must be highlighted that rat skeletal muscle TC increases ~ 5070% following 4 weeks of LC supplementation [33, 34], whereas comparable elevation has never been observed in human studies, even after 24 weeks of supplementation [5, 7]

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Activation of this pathway is delayed in older subjects [38], contributing to the decrease in protein synthesis with age

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