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doi: 10.3389/fnins.2015.00469

S.MaybrierH

Carnitine panel was abnormal in half of the patients in whom it was measured with 33% of the patients having high-esterified carnitine and 17% having low free carnitine

Supplementing carnitine in such cases is considered beneficial, especially since it is regarded as a 'conditionally essential nutrient' in patients on long-term TPN

In parallel, cultured hepatocyte models (alpha mouse liver 12 [AML12] cells) with RAP1A knockdown or overexpression were used to assess cellular lipid accumulation, fatty acid oxidation, and mechanistic pathways
