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JAMA 292 , 14401446 (2004)

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Considering nicotine use disorder (NUD), there are several data supporting beneficial effects of acute or chronic NAC treatment on nicotine reward assessed in self-administration or conditioned place preference rodent models [27, 35,36,37] (Table 1)

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Either source can predominate, depending upon the duration and intensity of exercise, degree of prior physical conditioning, and the composition of the diet consumed in the days before the exercise [52]