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Where required initial treatment is with chemotherapy with radiotherapy reserved for teenagers and younger children who have not responded to chemotherapy

Folate helps prevent neural tube defects, while iron supports red blood cell production

Since the drug candidate has already been translated into the clinic for several decades, its established pharmacological properties and safety and side-effect profiles expedite preclinical and clinical assessment for the treatment of COVID-19

An important process is nitric oxide inactivation through its reaction with superoxide radicals, which results in the formation of peroxynitrite ONOO