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They were randomly divided into three groups (three mice per group) and injected intravenously through the tail vein with free DOX/SOR, D/S@MM, and D/S@SPMM, with 5 mg DOX/kg and 1 mg SOR/kg

Excessive accumulation of ROS leads to oxidative damage to biomolecules (such as DNA, proteins, and lipids), thereby inducing oxidative stress in cells

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Extracellular matrix support: Promotes collagen, elastin & related structural proteins

BDNF mRNA 32% stressed Semax +18% above naive

10.1111/bph.12461 Summary Keywords sarcopenia, lipid peroxidation, oxidative stress, antioxidants, therapeutic strategies Citation Lu Y, Li T, Shu Y, Lu C, Luo Z, Wang J, Xiong H and Li W (2025) Lipid peroxidation and sarcopenia: molecular mechanisms and potential therapeutic approaches