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The disconnect between preclinical efficacy and human clinical outcomes remains unexplained and represents a significant limitation for potential therapeutic applications

While Vitamin B12 can be obtained from dietary sources such as meat, fish, dairy products, and fortified cereals, some individuals may have difficulty absorbing it due to medical conditions or dietary restrictions

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Series 1: obese C57BL/6J mice (high-fat diet) randomized to daily injections of hGH, AOD-9604, or placebo

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