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For others, especially if their levels have been low for a while, it can take a few weeks and more than one injection to feel the full benefit

10.1021/np900205m 278 ZhangY.WuY.-T.ZhengW.HanX.-X.JiangY.-H.HuP.-L.et al (2017)

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B-cell heterogeneity is also evident: CD24highCD38high B cells with regulatory potential inversely correlate with disease activity, whereas certain activated B-cell phenotypes are linked to disease exacerbation (Uzzan et al., 2022)