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The largest screening trial shows a 21% decrease in prostate cancer deaths

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Emerging imaging techniques show promise but remain investigational

However, the 1998 and 1999 version's ISBN number is the same (4 517331 150435), whereas the ISBN of the 2001 version is 4 529123 101044

It modulates matrix metalloproteinases (MMPs) alongside their tissue inhibitors (TIMPs), creating balanced extracellular matrix remodeling rather than simply suppressing collagen degradation