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While our current study provides significant insights into the neuroprotective role of Irisin through its modulation of microglia-induced neurotoxicity, it is important to acknowledge that exploring the involvement of astrocytes and the broader neuroimmune response remains beyond the scope of this manuscript

Lonnerdal Bo, & Rucker RB, Editors), Plenum Press, New York & London, 1988, pp.97-99

This process is tightly regulated and consists of two primary phases, acute and chronic inflammation 1,2

This underscores the importance of utilizing methods like the quartile-based IQR for a more accurate depiction of data spread

Moreover, the benefits of melatonin are appreciable in mitochondria isolated from aged rodent brains where chronic treatment allows for antiapoptotic effects and increased cellular respiration as the young mitochondria counterparts

coli gene homologues The proteins of E
