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First, PPI-induced hormonal changes, such as hypergastrinemia and hyperparathyroidism, affect intestinal osmolality as well as calcium and phosphorus metabolism, which in turn affect the intestinal flora (Yang and Metz, 2010)
Management of priapism: an update for clinicians
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229 Major surgery should be reserved for patients who have exhausted all other feasible options and whose symptoms are caused by the bladder
Probiotics can accelerate this cycle to achieve the goal of reducing cholesterol
