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Furthermore, glutathione is strictly required for the biochemical synthesis of DNA building blocks

Antidepressants for the treatment of chronic pain

doi: 10.1016/j.jad.2021.07.020

The binding of glutathione to the enzyme lowers its pKa value of thiol group from 9 to 6.4 [38], facilitating the deprotonation reaction

however, in recent years, researchers have begun to tap its potential for treating substance use and psychiatric disorders

10.1073/pnas.1423952112 136 WahlstrmA.SayinS
