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Description
The ratio of GSH:GSSG (glutathione redox ratio) is a sensitive index of oxidative stress, which can lead to a toxic imbalance between the production and removal of reactive oxygen species (ROS)
Presented at 20th annual ASHP midyear clinical meeting
Therefore, the excessive production of ROS is important to induce ferroptosis
References Sattler S (2017) The role of the immune system beyond the fight against infection
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These conditions trigger systemic inflammation, vascular injury, and increased production of proteins involved in the clotting process, including von Willebrand factor, tissue factor, and fibrinogen
