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The designed peptide (referred to as VGB4) was able to bind to both VEGFR1 and VEGFR2 on the Human Umbilical Vein Endothelial Cells (HUVECs) surface and inhibited VEGF-A driven proliferation, migration and tube formation in HUVECs through suppression of ERK1/2 and AKT phosphorylation

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Improved mitochondrial integrity and DNA repair

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Administration of this peptide has been associated with the release of serotonin in specific brain regions, notably the nigrostriatal areas, and has beneficial effects on dopaminergic systems