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They observed that the iGLP1-E2 conjugate prevented STZ-induced insulin-deficient diabetes, thereby demonstrating that, in vivo, the inactive GLP-1 was able to bind the GLP-1R and to direct E2 to -cells for protection

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Mechanism Inducing ferroptosis by suppressing system Xc- System Xc- is an amino acid antitransporter that is widely distributed in phospholipid bilayers
