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The metabolic amplification may increase both benefits and side effects

10.1038/nrc3829 156

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Chronic intraventricular administration of 1-methyl-4-phenylpyridinium as a progressive model of Parkinson's disease

Astrocyte glutamate transporters are increased in an early sporadic model of synucleinopathy
Lower SNCA transcripts might be a possible predictor of cognitive decline, and low SNCA transcripts were linked to early PD
