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In the PIP joint, extension is more limited because of the two so called check-rein ligaments, which attach the palmar plate to the proximal phalanx

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MPTP-induced mouse model of Parkinsons disease: a promising direction for therapeutic strategies

[DOI] [PubMed] [Google Scholar] 78.Novikov LN, Novikova LN, Mosahebi A, Wiberg M, Terenghi G, et al

Clinical trials show tirzepatide produces greater average weight loss (21% body weight) compared to semaglutide (17% body weight), thanks to its dual GIP/GLP-1 mechanism

Por eso sus efectos son perifricos: sobre oxidacin de grasa, metabolismo energtico muscular y recuperacin, pero no sobre cognicin