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Sulforaphane reduces hepatic glucose production and improves glucose control in patients with type 2 diabetes

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Targeted delivery of probiotics and their metabolites, based on the pathological link between intestinal microbiota metabolites and ferroptosis, may help inhibit ferroptosis, correct microbiota dysregulation, and restore immune homeostasis, offering a promising precision intervention strategy to alleviate IBD inflammation

Relative mRNA expression was determined using the GoTaq 1-step real-time quantitative PCR (RT-qPCR) system (TAKARA) and qPCR using SYBR premix Ex Taq kit (TAKARA), and RT-qPCR was performed on an ABI Prism 7500 Fast Real-Time PCR System (Applied Biosystems, CA, USA)

Furthermore, risk of deficiencies of key nutrients that are essential cofactors, such as folate and B12, for methylation and conversion of homocysteine may increase in prevalence postmenopausally, in response to disruptions to oestrogen levels (Vasquez-Lorenete et al., 2022)