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Looking at the PPARs heterodimerisation partner RXR, RXR ligands such as CD3264, TBT, or 9- cis retinoic acid are reported to interfere in reporter cell lines such as the HG5LN GAL4-PPAR, by decreasing the signal induced by the PPAR ligands according to their Kd for RXRs (59)

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[DOI] [PubMed] [Google Scholar] 23.Meador K.J., Penovich P., Baker G.A., Pennell P.B., Bromfield E., Pack A., Liporace J.D., Sam M., Kalayjian L.A., Thurman D.J., Moore E., Loring D.W

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Interestingly, lower adiponectin, which is associated with obesity, metabolic syndrome, IR and cancer [261,262,263,264,265,266,267,268,269,270,271], was detected more often in digested microclots of LC patients compared to the control group [203]

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