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Typically occurring between ages 45 and 55, perimenopause transition is characterized by fluctuating estrogen levels and declining ovarian function that initiate a cascade of physiological and psychological changes that extend far beyond reproductive health

N Engl J Med 348:383393 Gaede P, Lund-Andersen H, Parving HH, Pedersen O (2008) Effect of a multifactorial intervention on mortality in type 2 diabetes

However, these medications are not subject to FDA approval and are not evaluated for safety or effectiveness

The venture-backed group has raised a combined $2.8 billion in funding, reflecting the intense investor appetite in the category

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Don't let low-appetite days become zero-protein days that's where muscle loss accelerates fastest