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Schleh, M

Significantly more patients achieved the co-primary endpoint of 5% body weight reduction with tirzepatide MTD (87.5% for the TRE and 94.4% for the efficacy estimand) than with placebo (16.5% for the TRE and 10.7% for the efficacy estimand

AWARD-7 enrolled adult patients with T2D (A1c, 7.5%10.5%) and CKD stages 34 who were being treated with ACEi or ARBs and found that dulaglutide (0.75 or 1.5 mg subcutaneous once weekly) achieved similar glycemic control to insulin glargine but had significantly less eGFR decline (mean 0.7 vs 3.3 mL/min/1.73 m 2 , respectively
