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Sustained Energy: No spikes or crashesjust steady, balanced energy throughout the day

Some patients view these medications as temporary tools to jumpstart weight loss, while others accept them as long-term management for a chronic condition

In the Phase 2 obesity trial, retatrutide 12 mg produced approximately 24.2% mean weight loss at 48 weeks ( Jastreboff et al., NEJM 2023 ), and the Phase 2 type 2 diabetes trial showed strong HbA1c and weight reductions ( Rosenstock et al., Lancet 2023 )

There were comparable reductions in AHI per unit decrease in BMI across various weight loss interventions including life-style changes, medications, or bariatric surgery [65]

The subcutaneous fat layer ensures the medication is absorbed slowly and steadily, allowing it to work as intended over time

In terms of its risk-benefit profile, retatrutide is looking like a powerful obesity drug with the potential benefit of strengthening its position helping those with diabetes