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Those in the treatment group additionally received Jiawei Yueju Decoction, whose main active ingredients include geniposide, the main components of iridoids, which had been demonstrated to reduce blood glucose levels in mice in a dose-dependent manner

This approval was based on clinical trials demonstrating the safety and efficacy of liraglutide in this age group, offering a new treatment option for adolescents with obesity who have not responded adequately to lifestyle interventions alone [18]

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doi: 10.1371/journal.pone.0001709 157 RozhdestvenskyTSRobeckTGalivetiCRRaabeCASeegerBWoltersAet al