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The interaction of HKDC1 with VDAC1 enhances mitochondrial outer membrane contacts with lysosomal transient receptor potential cation channel mucolipin subfamily member 1 (TRPML1)

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Interestingly, the metabolic dysregulation induced by an HFD manifests multifaceted pathogenic effects

Medical management is key to prevention progressive disease, but surgical management is usually necessary when a person has painful joint destruction and/or tendon ruptures
