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Description
Appetite suppression can make hitting protein targets challenging

sygl-1(q828) , 11 1 (n = 49)

Delayed absorption of narrow-therapeutic-index drugs (e.g., warfarin, levothyroxine, some antiepileptics) can occur

Addressing equity issues is critical to ensure that all individuals, regardless of socioeconomic status, can benefit from these advancements in obesity treatment

(Lausanne) 13 , 846903 (2022)

Here we report high-resolution cryo-electron microscopy (cryo-EM) structures of human GLP-1RG s in complex with compound 2 alone, with both compound 2 and endogenous peptidic agonist GLP-1, or with compound 2 and a small molecule agonist (LY3502970)
