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Neurology 57, 245254

Probiotics and antimicrobial proteins

doi: 10.1016/j.semcancer.2012.01.011 146 Garca-NavasRMunderMMollinedoF

This binding can upregulate or downregulate their gene expression through various mechanisms

The transcription factor cAMP response element modulator (CREM) is highly expressed in male germ cells and regulates the expression of several post-meiotic genes, such as the transition proteins and protamines, and it likely is the key regulator of gene expression during spermatogenesis

Iron-dependent enzymes known to drive ferroptosis include lipoxygenases (LOX), cyclooxygenases (COX), and cytochrome P450 oxidoreductases (POR) [53,54,55,56], all of which catalyse the formation of bioactive LOOH, which regulates cellular signalling